CBD Isolate and Autoimmune Diseases: The Risks of Using THC

benefici del cbd per cura delle malattie autoimmuni rischi del thc

THC-Free CBD Isolate: Agrilab's Revolutionary Cry

The therapeutic revolution has begun. And it starts from a clear principle: when it comes to cognitive health, THC is not the answer.

We at AgriLab , the only Italian company producing THC-free CBD isolate , are raising our voice for a new vision of therapeutic cannabis: ethical, scientific, and without side effects.

Autoimmune diseases such as lupus , rheumatoid arthritis or Sjögren's syndrome affect millions of people and are characterised by an immune system that, instead of protecting the body, attacks it.

In this delicate balance, choosing the right cannabinoid can make all the difference . And this is where CBD isolate , free of THC, emerges as the only safe, legal, and customizable option .

CBD Isolate and Autoimmune Diseases: Why You Should Avoid THC

The endocannabinoid system and the control of immunity

The endocannabinoid system (ECS) is a regulatory network that constantly communicates with the immune system. It acts through several receptors:

  • CB2 : on lymphocytes, macrophages and dendritic cells – regulates inflammation.

  • PPARγ : controls the balance between pro-inflammatory (Th17) and regulatory (Treg) cells.

  • A2A : promotes immunological tolerance in tissues.

  • TRPV1 : mediates inflammatory pain.

  • Pro-inflammatory cytokines such as IL-6, IL-17, TNF-α, are the enemies to be appeased.

CBD Isolate: Accuracy, Safety, Effectiveness

CBD isolate is the only legal cannabinoid in Italy capable of:

  • Modulate CB2 → stimulates tolerance, reduces IL-6 and TNF-α.

  • Activate PPARγ → rebalances Th17/Treg, reduces inflammation.

  • Interacts with A2A → strengthens the peripheral regulatory system.

  • Desensitizing TRPV1 → reduces chronic pain.

  • Act as an antioxidant → protects against tissue damage.

🎯 Result? A smart response: it calms the immune system without shutting it down .

The Limits of THC: Suppression, Not Regulation

THC also acts on CB2 receptors, but in a non-selective way:

  • It suppresses the entire immune system , not just the harmful responses.

  • The risk of infection increases.

  • It does not modulate PPARγ or A2A.

  • It causes sedation, cognitive impairment , anxiety and difficulty in daily management.

  • It worsens the quality of life of already fragile patients.

THC is not suitable for the chronic management of autoimmune diseases.

🔍 CBD Isolate vs. THC: Fine Immunomodulation vs. Crude Suppression

Characteristic CBD Isolate THC
Immune effect Selective Th17/Treg regulation Nonspecific suppression
Infectious risk Nobody High
Psychoactive effects Absent Present (confusion, sedation)
Legality ✅ Legal and certified ❌ At legal and regulatory risk
Therapeutic adaptability High – even in the long term Low – limited tolerability

Conclusion

Those living with an autoimmune disease need a safe, stable, and truly effective solution . CBD isolate is currently the only cannabinoid:

  • Legally usable

  • Free of side effects

  • Suitable for long-term immunological support

Avoid THC: it is useless , and in many cases it can worsen symptoms.

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Scientific sources

Want to find out how CBD Isolate can help with various conditions?

👉 Keep following us on the blog : in the next articles we will talk about all the pathologies that can be supported by CBD isolate.

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💚 Health is our most precious asset. It's time to take care of it more consciously and naturally!

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Read also the other articles on our blog

Cannabis: History of its origins and the difference between CBD and THC

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